Effect of Methyl Testosterone on Urinary 17-ketosteroids of Adrenal Origin.
نویسندگان
چکیده
منابع مشابه
Regulatory Modifications of Steroidogenesis following the Administration of Embryonary Peptides
Regulatory modifications of steroidogenesis were induced following the administration on rats and humans of a nutritive supplement, Humanofort, containing two embryonary peptides (EP) of 5 and 10 kDa. The administration of EP to rats for 60 days increased significantly the urinary excretion of 17-ketosteroids in all animals. The serum cholesterol increased only in females, by ~50%, this increas...
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Adrenal cortical hyperplasia which is known to occur during infection and after trauma (1, 2) suggests the occurrence of a corresponding increase in the physiological activity of the gland. Scant information is available, however, bearing directly on the functional status of the adrenal cortex during conditions of stress. It would be important to know not only whether periods of stress are acco...
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Cholesterol and ascorbic acid of adrenals are significantly diminished in scorbutic guinea pigs (1). As these substances appear to be related to the formation of adrenal cortical hormone (a), it has been indicated that the secretion of this hormone might diminish in scurvy. The urinary excretion of 17-ketosteroids in females is said to depend almost entirely on the activity of the adrenal corte...
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The evidence of the literature indicates that the adrenal cortex produces a variety of hormones, some of which, like desoxycorticosterone, act predominantly to maintain a normal water and electrolyte balance (1), while others, like corticosterone, are effective chiefly through preventing hypoglycemia, either by facilitating the formation of sugar from protein (gluconeogenesis) (2) or by inhibit...
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We describe here a typical case of virilizing adrenocortical tumor. A 23-year-old Japanese woman had her male-like musculature, hirsutism, the absence of breast development and marked clitoromegaly. Adrenal androgens were remarkably elevated, with plasma dehydroepiandrosterone sulfate 2,752 micrograms/dl, plasma testosterone 250 ng/dl and urinary 17-ketosteroids 203.4 mg/day. A well-encapsulate...
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ورودعنوان ژورنال:
- The Journal of clinical investigation
دوره 24 4 شماره
صفحات -
تاریخ انتشار 1945